Dynamic Diagnosis of Familial Prion Diseases Supports the β2-α2 Loop as a Universal Interference Target

Open Access

Peer-reviewed

Research Article

Massimiliano Meli,

Affiliation Department of Computational Biology, Istituto di Chimica del Riconoscimento Molecolare, Consiglio Nazionale delle Ricerche, Milano, Italy
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Maria Gasset ,

* E-mail: g.colombo@icrm.cnr.it (GC); mgasset@iqfr.csic.es (MG)

Affiliation Department of Biological Physical Chemistry, Instituto Química-Física “Rocasolano”, Consejo Superior de Investigaciones Científicas, Madrid, Spain
⨯
Giorgio Colombo

* E-mail: g.colombo@icrm.cnr.it (GC); mgasset@iqfr.csic.es (MG)

Affiliation Department of Computational Biology, Istituto di Chimica del Riconoscimento Molecolare, Consiglio Nazionale delle Ricerche, Milano, Italy
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Methionine
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Oxidation
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Substitution mutation
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Protein interactions
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Drug interactions
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Molecular dynamics
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Point mutation
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Prion diseases
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