Breaking Up the C Complex Spliceosome Shows Stable Association of Proteins with the Lariat Intron Intermediate

Open Access

Peer-reviewed

Research Article

Patricia Coltri,

Current address: Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil

Affiliations Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America, Center for Molecular Biology of RNA, University of California Santa Cruz, Santa Cruz, California, United States of America
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Kerstin Effenberger,

Affiliations Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America, Center for Molecular Biology of RNA, University of California Santa Cruz, Santa Cruz, California, United States of America
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Robert J. Chalkley,

Affiliation Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America
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A. L. Burlingame,

Affiliation Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America
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Melissa S. Jurica

* E-mail: jurica@biology.ucsc.edu

Affiliations Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America, Center for Molecular Biology of RNA, University of California Santa Cruz, Santa Cruz, California, United States of America
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Urea
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Spliceosomes
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Small nuclear RNA
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Glycerol
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Protein interactions
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Elution
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Introns
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RNA splicing
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