Rapid Temporal Control of Foxp3 Protein Degradation by Sirtuin-1

Open Access

Peer-reviewed

Research Article

Jorg van Loosdregt,

Affiliations Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands, Center for Molecular & Cellular Intervention, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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Diede Brunen,

Affiliations Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Cell Biology, University Medical Center Utrecht, Utrecht, The Netherlands
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Veerle Fleskens,

Affiliations Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Cell Biology, University Medical Center Utrecht, Utrecht, The Netherlands
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Cornelieke E. G. M. Pals,

Affiliations Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Cell Biology, University Medical Center Utrecht, Utrecht, The Netherlands
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Eric W. F. Lam,

Affiliation CR-UK Labs and Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, United Kingdom
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Paul J. Coffer

* E-mail: p.j.coffer@umcutrecht.nl

Affiliations Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands, Center for Molecular & Cellular Intervention, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Cell Biology, University Medical Center Utrecht, Utrecht, The Netherlands
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Regulatory T cells
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Transfection
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Acetylation
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Immunoprecipitation
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T cells
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Lysine
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Messenger RNA
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Protein expression
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