Dispersal of Group A Streptococcal Biofilms by the Cysteine Protease SpeB Leads to Increased Disease Severity in a Murine Model

Open Access

Peer-reviewed

Research Article

Kristie L. Connolly,

Affiliation Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
Amity L. Roberts,

Affiliation Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
Robert C. Holder,

Affiliation Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
Sean D. Reid

* E-mail: sreid@wfubmc.edu

Affiliation Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
⨯

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Bacterial biofilms
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Abscesses
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Animal models of infection
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Extracellular matrix proteins
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Group A streptococcal infection
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Soft tissue infections
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Biofilms
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Skin infections
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