Structural Basis for Dual-Inhibition Mechanism of a Non-Classical Kazal-Type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin

• Rajesh T. Shenoy,

  Affiliation Department of Biological Sciences, National University of Singapore, Singapore, Singapore

  ⨯
• Saravanan Thangamani,

  Affiliations Department of Biological Sciences, National University of Singapore, Singapore, Singapore, Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America

  ⨯
• Adrian Velazquez-Campoy,

  Affiliations Institute of Biocomputation and Physics of Complex Systems (BIFI), Universidad de Zaragoza, Zaragoza, Spain, Fundacion ARAID, Diputacion General de Aragon, Zaragoza, Spain

  ⨯
• Bow Ho,

  Affiliation Department of Microbiology, National University of Singapore, Singapore, Singapore

  ⨯
• Jeak Ling Ding ,

  * E-mail: dbsjayar@nus.edu.sg (JS); dbsdjl@nus.edu.sg (JLD)

  Affiliation Department of Biological Sciences, National University of Singapore, Singapore, Singapore

  ⨯
• J. Sivaraman

  * E-mail: dbsjayar@nus.edu.sg (JS); dbsdjl@nus.edu.sg (JLD)

  Affiliation Department of Biological Sciences, National University of Singapore, Singapore, Singapore

  ⨯