TLR2-Dependent Induction of IL-10 and Foxp3⁺CD25⁺CD4⁺ Regulatory T Cells Prevents Effective Anti-Tumor Immunity Induced by Pam2 Lipopeptides In Vivo

• Sayuri Yamazaki ,

  Contributed equally to this work with: Sayuri Yamazaki, Kohei Okada

  * E-mail: seya-tu@pop.med.hokudai.ac.jp (TS); yamazas@med.hokudai.ac.jp (SY)

  Affiliation Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

  ⨯
• Kohei Okada ,

  Contributed equally to this work with: Sayuri Yamazaki, Kohei Okada

  Affiliation Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

  ⨯
• Akira Maruyama,

  Affiliation Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

  ⨯
• Misako Matsumoto,

  Affiliation Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

  ⨯
• Hideo Yagita,

  Affiliation Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan

  ⨯
• Tsukasa Seya

  * E-mail: seya-tu@pop.med.hokudai.ac.jp (TS); yamazas@med.hokudai.ac.jp (SY)

  Affiliation Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

  ⨯