Ubiquitin Fold Modifier 1 (UFM1) and Its Target UFBP1 Protect Pancreatic Beta Cells from ER Stress-Induced Apoptosis

Katleen Lemaire; Rodrigo F. Moura; Mikaela Granvik; Mariana Igoillo-Esteve; Hans E. Hohmeier; Nico Hendrickx; Christopher B. Newgard; Etienne Waelkens; Miriam Cnop; Frans Schuit

doi:10.1371/journal.pone.0018517

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Peer-reviewed

Research Article

Ubiquitin Fold Modifier 1 (UFM1) and Its Target UFBP1 Protect Pancreatic Beta Cells from ER Stress-Induced Apoptosis

Katleen Lemaire ,

Contributed equally to this work with: Katleen Lemaire, Rodrigo F. Moura

* E-mail: katleen.lemaire@med.kuleuven.be (KL); frans.schuit@med.kuleuven.be (FS)

Affiliation Gene Expression Unit, Department Molecular Cell Biology, KatholiekeUniversiteit Leuven, Leuven, Belgium
⨯
Rodrigo F. Moura ,

Contributed equally to this work with: Katleen Lemaire, Rodrigo F. Moura

Affiliation Laboratory of Experimental Medicine, Université Libre de Bruxelles, Brussels, Belgium
⨯
Mikaela Granvik,

Affiliation Gene Expression Unit, Department Molecular Cell Biology, KatholiekeUniversiteit Leuven, Leuven, Belgium
⨯
Mariana Igoillo-Esteve,

Affiliations Laboratory of Experimental Medicine, Université Libre de Bruxelles, Brussels, Belgium, Division of Endocrinology, Erasmus Hospital, Brussels, Belgium
⨯
Hans E. Hohmeier,

Affiliation Sarah W. Stedman Nutrition and Metabolism Center and Departments of Pharmacology and Cancer Biology and Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Nico Hendrickx,

Affiliation Gene Expression Unit, Department Molecular Cell Biology, KatholiekeUniversiteit Leuven, Leuven, Belgium
⨯
Christopher B. Newgard,

Affiliation Sarah W. Stedman Nutrition and Metabolism Center and Departments of Pharmacology and Cancer Biology and Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Etienne Waelkens,

Affiliation Prometa, Department Molecular Cell Biology, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Miriam Cnop,

Affiliations Laboratory of Experimental Medicine, Université Libre de Bruxelles, Brussels, Belgium, Division of Endocrinology, Erasmus Hospital, Brussels, Belgium
⨯
Frans Schuit

* E-mail: katleen.lemaire@med.kuleuven.be (KL); frans.schuit@med.kuleuven.be (FS)

Affiliation Gene Expression Unit, Department Molecular Cell Biology, KatholiekeUniversiteit Leuven, Leuven, Belgium
⨯

Ubiquitin Fold Modifier 1 (UFM1) and Its Target UFBP1 Protect Pancreatic Beta Cells from ER Stress-Induced Apoptosis

Katleen Lemaire,
Rodrigo F. Moura,
Mikaela Granvik,
Mariana Igoillo-Esteve,
Hans E. Hohmeier,
Nico Hendrickx,
Christopher B. Newgard,
Etienne Waelkens,
Miriam Cnop,
Frans Schuit

Published: April 6, 2011
https://doi.org/10.1371/journal.pone.0018517

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