Prediction of Antimicrobial Peptides Based on Sequence Alignment and Feature Selection Methods

Ping Wang; Lele Hu; Guiyou Liu; Nan Jiang; Xiaoyun Chen; Jianyong Xu; Wen Zheng; Li Li; Ming Tan; Zugen Chen; Hui Song; Yu-Dong Cai; Kuo-Chen Chou

doi:10.1371/journal.pone.0018476

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Open Access

Peer-reviewed

Research Article

Prediction of Antimicrobial Peptides Based on Sequence Alignment and Feature Selection Methods

Ping Wang,

Affiliation Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China
⨯
Lele Hu,

Affiliations Institute of Systems Biology, Shanghai University, Shanghai, China, Department of Chemistry, College of Sciences, Shanghai University, Shanghai, China
⨯
Guiyou Liu,

Affiliation Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China
⨯
Nan Jiang,

Affiliation Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China
⨯
Xiaoyun Chen,

Affiliation Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China
⨯
Jianyong Xu,

Affiliation Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China
⨯
Wen Zheng,

Affiliation Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China
⨯
Li Li,

Affiliation Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China
⨯
Ming Tan,

Affiliation Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China
⨯
Zugen Chen,

Affiliations Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China, Department of Human Genetics, University of California Los Angeles, Los Angeles, California, United States of America
⨯
Hui Song ,

* E-mail: song_h@tib.cas.cn (HS); cai_yud@yahoo.com.cn (Y-DC)

Affiliation Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China
⨯
Yu-Dong Cai ,

* E-mail: song_h@tib.cas.cn (HS); cai_yud@yahoo.com.cn (Y-DC)

Affiliations Institute of Systems Biology, Shanghai University, Shanghai, China, Department of Chemistry, College of Sciences, Shanghai University, Shanghai, China, Gordon Life Science Institute, San Diego, California, United States of America
⨯
Kuo-Chen Chou

Affiliation Gordon Life Science Institute, San Diego, California, United States of America
⨯

Prediction of Antimicrobial Peptides Based on Sequence Alignment and Feature Selection Methods

Ping Wang,
Lele Hu,
Guiyou Liu,
Nan Jiang,
Xiaoyun Chen,
Jianyong Xu,
Wen Zheng,
Li Li,
Ming Tan,
Zugen Chen

Published: April 13, 2011
https://doi.org/10.1371/journal.pone.0018476

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Sequence alignment
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Protein sequencing
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Antimicrobials
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Forecasting
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Algorithms
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Amino acid analysis
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BLAST algorithm
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Support vector machines
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