Activation of Neural and Pluripotent Stem Cell Signatures Correlates with Increased Malignancy in Human Glioma

Johan Holmberg; Xiaobing He; Inti Peredo; Abiel Orrego; Göran Hesselager; Christer Ericsson; Outi Hovatta; Sueli Mieko Oba-Shinjo; Suely Kazue Nagahashi Marie; Monica Nistér; Jonas Muhr

doi:10.1371/journal.pone.0018454

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Open Access

Peer-reviewed

Research Article

Activation of Neural and Pluripotent Stem Cell Signatures Correlates with Increased Malignancy in Human Glioma

Johan Holmberg ,

Contributed equally to this work with: Johan Holmberg, Xiaobing He

* E-mail: johan.holmberg@licr.ki.se (JH); jonas.muhr@licr.ki.se (JM)

Affiliations Ludwig Institute for Cancer Research, Karolinska Institutet, Stockholm, Sweden, Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
⨯
Xiaobing He ,

Contributed equally to this work with: Johan Holmberg, Xiaobing He

Affiliation Department of Oncology-Pathology, Karolinska Institutet, CCK R8:05, Karolinska University Hospital Solna, Stockholm, Sweden
⨯
Inti Peredo,

Affiliation Department of Clinical Neuroscience, Neurosurgery, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
⨯
Abiel Orrego,

Affiliation Department of Oncology-Pathology, Karolinska Institutet, CCK R8:05, Karolinska University Hospital Solna, Stockholm, Sweden
⨯
Göran Hesselager,

Affiliation Department of Neuroscience, Neurosurgery, Uppsala University, University Hospital, Uppsala, Sweden
⨯
Christer Ericsson,

Affiliation Department of Oncology-Pathology, Karolinska Institutet, CCK R8:05, Karolinska University Hospital Solna, Stockholm, Sweden
⨯
Outi Hovatta,

Affiliation Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
⨯
Sueli Mieko Oba-Shinjo,

Affiliation Department of Neurology, School of Medicine, University of Sao Paulo, São Paulo, Brazil
⨯
Suely Kazue Nagahashi Marie,

Affiliation Department of Neurology, School of Medicine, University of Sao Paulo, São Paulo, Brazil
⨯
Monica Nistér,

Affiliation Department of Oncology-Pathology, Karolinska Institutet, CCK R8:05, Karolinska University Hospital Solna, Stockholm, Sweden
⨯
Jonas Muhr

* E-mail: johan.holmberg@licr.ki.se (JH); jonas.muhr@licr.ki.se (JM)

Affiliations Ludwig Institute for Cancer Research, Karolinska Institutet, Stockholm, Sweden, Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
⨯

Activation of Neural and Pluripotent Stem Cell Signatures Correlates with Increased Malignancy in Human Glioma

Johan Holmberg,
Xiaobing He,
Inti Peredo,
Abiel Orrego,
Göran Hesselager,
Christer Ericsson,
Outi Hovatta,
Sueli Mieko Oba-Shinjo,
Suely Kazue Nagahashi Marie,
Monica Nistér

Published: March 31, 2011
https://doi.org/10.1371/journal.pone.0018454

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