Antiviral Activity of 3(2H)- and 6-Chloro-3(2H)-Isoflavenes against Highly Diverged, Neurovirulent Vaccine-Derived, Type2 Poliovirus Sewage Isolates

Lester M. Shulman; Danit Sofer; Yossi Manor; Ella Mendelson; Jean Balanant; Anna Laura Salvati; Francis Delpeyroux; Lucia Fiore

doi:10.1371/journal.pone.0018360

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Peer-reviewed

Research Article

Antiviral Activity of 3(2H)- and 6-Chloro-3(2H)-Isoflavenes against Highly Diverged, Neurovirulent Vaccine-Derived, Type2 Poliovirus Sewage Isolates

Lester M. Shulman ,

* E-mail: lester.shulman@sheba.health.gov.il

Affiliations Central Virology Laboratory, Public Health Services Israel Ministry of Health, Chaim Sheba Medical Center, Tel Hashomer, Israel, Department of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, University of Tel Aviv, Ramat Gan, Israel
⨯
Danit Sofer,

Affiliation Central Virology Laboratory, Public Health Services Israel Ministry of Health, Chaim Sheba Medical Center, Tel Hashomer, Israel
⨯
Yossi Manor,

Affiliation Central Virology Laboratory, Public Health Services Israel Ministry of Health, Chaim Sheba Medical Center, Tel Hashomer, Israel
⨯
Ella Mendelson,

Affiliations Central Virology Laboratory, Public Health Services Israel Ministry of Health, Chaim Sheba Medical Center, Tel Hashomer, Israel, Department of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, University of Tel Aviv, Ramat Gan, Israel
⨯
Jean Balanant,

Affiliations Biology of Enteric Viruses, Institut Pasteur, Paris, France, Institut National de la Santé et de la Recherche Médicale (INSERM) U994, Paris, France
⨯
Anna Laura Salvati,

Affiliation National Center for Immunobiologicals Research and Evaluation (CRIVIB), Istituto Superiore di Sanità, Viale Regina Elena, Rome, Italy
⨯
Francis Delpeyroux,

Affiliations Biology of Enteric Viruses, Institut Pasteur, Paris, France, Institut National de la Santé et de la Recherche Médicale (INSERM) U994, Paris, France
⨯
Lucia Fiore

Affiliation National Center for Immunobiologicals Research and Evaluation (CRIVIB), Istituto Superiore di Sanità, Viale Regina Elena, Rome, Italy
⨯

Antiviral Activity of 3(2H)- and 6-Chloro-3(2H)-Isoflavenes against Highly Diverged, Neurovirulent Vaccine-Derived, Type2 Poliovirus Sewage Isolates

Lester M. Shulman,
Danit Sofer,
Yossi Manor,
Ella Mendelson,
Jean Balanant,
Anna Laura Salvati,
Francis Delpeyroux,
Lucia Fiore

Published: May 25, 2011
https://doi.org/10.1371/journal.pone.0018360

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