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Open Access

Peer-reviewed

Research Article

Carotid Plaque Age Is a Feature of Plaque Stability Inversely Related to Levels of Plasma Insulin

Sara Hägg,

Affiliations The Cardiovascular Genomics Group, Department of Medical Biochemistry and Biophysics, Solna, Karolinska Institutet, Stockholm, Sweden, Clinical Gene Networks AB, Stockholm, Sweden
⨯
Mehran Salehpour,

Affiliation Ion Physics, Department of Physics and Astronomy, Uppsala University, Uppsala, Sweden
⨯
Peri Noori,

Affiliation The Computational Medicine Group, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
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Jesper Lundström,

Affiliations The Cardiovascular Genomics Group, Department of Medical Biochemistry and Biophysics, Solna, Karolinska Institutet, Stockholm, Sweden, Clinical Gene Networks AB, Stockholm, Sweden
⨯
Göran Possnert,

Affiliation Ion Physics, Department of Physics and Astronomy, Uppsala University, Uppsala, Sweden
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Rabbe Takolander,

Affiliation Department of Surgery, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden
⨯
Peter Konrad,

Affiliation Department of Surgery, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden
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Stefan Rosfors,

Affiliation Department of Clinical Physiology, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden
⨯
Arno Ruusalepp,

Affiliation Department of Cardiac Surgery, Tartu University Hospital, Tartu, Estonia
⨯
Josefin Skogsberg,

Affiliations The Cardiovascular Genomics Group, Department of Medical Biochemistry and Biophysics, Solna, Karolinska Institutet, Stockholm, Sweden, Clinical Gene Networks AB, Stockholm, Sweden
⨯
Jesper Tegnér,

Affiliation The Computational Medicine Group, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
⨯
Johan Björkegren

* E-mail: Johan.Bjorkegren@ki.se

Affiliations The Cardiovascular Genomics Group, Department of Medical Biochemistry and Biophysics, Solna, Karolinska Institutet, Stockholm, Sweden, Clinical Gene Networks AB, Stockholm, Sweden
⨯

Carotid Plaque Age Is a Feature of Plaque Stability Inversely Related to Levels of Plasma Insulin

Sara Hägg,
Mehran Salehpour,
Peri Noori,
Jesper Lundström,
Göran Possnert,
Rabbe Takolander,
Peter Konrad,
Stefan Rosfors,
Arno Ruusalepp,
Josefin Skogsberg

x

Published: April 7, 2011
https://doi.org/10.1371/journal.pone.0018248

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Insulin
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Atherosclerosis
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Gene expression
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Blood plasma
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Collagens
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Lipoproteins
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Macrophages
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Stenosis
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