In Vitro Amplification of Misfolded Prion Protein Using Lysate of Cultured Cells

Charles E. Mays; Jihyun Yeom; Hae-Eun Kang; Jifeng Bian; Vadim Khaychuk; Younghwan Kim; Jason C. Bartz; Glenn C. Telling; Chongsuk Ryou

doi:10.1371/journal.pone.0018047

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Peer-reviewed

Research Article

In Vitro Amplification of Misfolded Prion Protein Using Lysate of Cultured Cells

Charles E. Mays,

Current address: Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada

Affiliation Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America
⨯
Jihyun Yeom,

Affiliation Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America
⨯
Hae-Eun Kang,

Affiliation Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America
⨯
Jifeng Bian,

Affiliation Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America
⨯
Vadim Khaychuk,

Affiliation Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America
⨯
Younghwan Kim,

Current address: Department of Neurobiology and Anatomy, University of Utah, Salt Lake City, Utah, United States of America

Affiliation Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America
⨯
Jason C. Bartz,

Affiliation Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America
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Glenn C. Telling,

Affiliations Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America, Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America
⨯
Chongsuk Ryou

* E-mail: cryou2@email.uky.edu

Affiliations Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America, Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America
⨯

In Vitro Amplification of Misfolded Prion Protein Using Lysate of Cultured Cells

Charles E. Mays,
Jihyun Yeom,
Hae-Eun Kang,
Jifeng Bian,
Vadim Khaychuk,
Younghwan Kim,
Jason C. Bartz,
Glenn C. Telling,
Chongsuk Ryou

Published: March 28, 2011
https://doi.org/10.1371/journal.pone.0018047

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