p53 Regulates Oxidative Stress-Mediated Retrograde Signaling: A Novel Mechanism for Chemotherapy-Induced Cardiac Injury

Joyce M. Velez; Sumitra Miriyala; Ramaneeya Nithipongvanitch; Teresa Noel; Chotiros D. Plabplueng; Terry Oberley; Paiboon Jungsuwadee; Holly Van Remmen; Mary Vore; Daret K. St. Clair

doi:10.1371/journal.pone.0018005

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Peer-reviewed

Research Article

p53 Regulates Oxidative Stress-Mediated Retrograde Signaling: A Novel Mechanism for Chemotherapy-Induced Cardiac Injury

Joyce M. Velez ,

Contributed equally to this work with: Joyce M. Velez, Sumitra Miriyala

Affiliation Graduate Center for Toxicology, University of Kentucky, Lexington, Kentucky, United States of America
⨯
Sumitra Miriyala ,

Contributed equally to this work with: Joyce M. Velez, Sumitra Miriyala

Affiliation Graduate Center for Toxicology, University of Kentucky, Lexington, Kentucky, United States of America
⨯
Ramaneeya Nithipongvanitch,

Affiliation The Faculty of Medical Technology, Mahidol University, Bangkok, Thailand
⨯
Teresa Noel,

Affiliation Graduate Center for Toxicology, University of Kentucky, Lexington, Kentucky, United States of America
⨯
Chotiros D. Plabplueng,

Affiliation The Faculty of Medical Technology, Mahidol University, Bangkok, Thailand
⨯
Terry Oberley,

Affiliations Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, Wisconsin, United States of America, Pathology and Laboratory Medicine Service, William S. Middleton Memorial Veterans Administration Hospital, Madison, Wisconsin, United States of America
⨯
Paiboon Jungsuwadee,

Affiliation Graduate Center for Toxicology, University of Kentucky, Lexington, Kentucky, United States of America
⨯
Holly Van Remmen,

Affiliation Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯
Mary Vore,

Affiliation Graduate Center for Toxicology, University of Kentucky, Lexington, Kentucky, United States of America
⨯
Daret K. St. Clair

* E-mail: DSTCL00@uky.edu

Affiliation Graduate Center for Toxicology, University of Kentucky, Lexington, Kentucky, United States of America
⨯

p53 Regulates Oxidative Stress-Mediated Retrograde Signaling: A Novel Mechanism for Chemotherapy-Induced Cardiac Injury

Joyce M. Velez,
Sumitra Miriyala,
Ramaneeya Nithipongvanitch,
Teresa Noel,
Chotiros D. Plabplueng,
Terry Oberley,
Paiboon Jungsuwadee,
Holly Van Remmen,
Mary Vore,
Daret K. St. Clair

Published: March 30, 2011
https://doi.org/10.1371/journal.pone.0018005

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