Location of Immunization and Interferon-γ Are Central to Induction of Salivary Gland Dysfunction in Ro60 Peptide Immunized Model of Sjögren's Syndrome

Hongen Yin; Jelle L. Vosters; Nienke Roescher; Anil D'Souza; Biji T. Kurien; Paul P. Tak; John A. Chiorini

doi:10.1371/journal.pone.0018003

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Peer-reviewed

Research Article

Location of Immunization and Interferon-γ Are Central to Induction of Salivary Gland Dysfunction in Ro60 Peptide Immunized Model of Sjögren's Syndrome

Hongen Yin ,

Contributed equally to this work with: Hongen Yin, Jelle L. Vosters

Affiliation Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Jelle L. Vosters ,

Contributed equally to this work with: Hongen Yin, Jelle L. Vosters

Affiliations Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America, Division of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Nienke Roescher,

Affiliations Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America, Division of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Anil D'Souza,

Affiliation Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
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Biji T. Kurien,

Affiliation Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
⨯
Paul P. Tak,

Affiliation Division of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
John A. Chiorini

* E-mail: jchiorini@dir.nidcr.nih.gov

Affiliation Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Location of Immunization and Interferon-γ Are Central to Induction of Salivary Gland Dysfunction in Ro60 Peptide Immunized Model of Sjögren's Syndrome

Hongen Yin,
Jelle L. Vosters,
Nienke Roescher,
Anil D'Souza,
Biji T. Kurien,
Paul P. Tak,
John A. Chiorini

Published: March 28, 2011
https://doi.org/10.1371/journal.pone.0018003

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