Identification and Replication of Loci Involved in Camptothecin-Induced Cytotoxicity Using CEPH Pedigrees

Venita Gresham Watson; Alison Motsinger-Reif; Nicholas E. Hardison; Eric J. Peters; Tammy M. Havener; Lorraine Everitt; James Todd Auman; Daniel L. Comins; Howard L. McLeod

doi:10.1371/journal.pone.0017561

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Peer-reviewed

Research Article

Identification and Replication of Loci Involved in Camptothecin-Induced Cytotoxicity Using CEPH Pedigrees

Venita Gresham Watson,

Affiliation Division of Pharmacotherapy and Experimental Therapeutics, Institute for Pharmacogenomics and Individualized Therapy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
⨯
Alison Motsinger-Reif,

Affiliation Department of Statistics, Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Nicholas E. Hardison,

Affiliation Department of Statistics, Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Eric J. Peters,

Affiliation Division of Pharmacotherapy and Experimental Therapeutics, Institute for Pharmacogenomics and Individualized Therapy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Tammy M. Havener,

Affiliation Division of Pharmacotherapy and Experimental Therapeutics, Institute for Pharmacogenomics and Individualized Therapy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
⨯
Lorraine Everitt,

Affiliation Division of Pharmacotherapy and Experimental Therapeutics, Institute for Pharmacogenomics and Individualized Therapy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
⨯
James Todd Auman,

Affiliation Division of Pharmacotherapy and Experimental Therapeutics, Institute for Pharmacogenomics and Individualized Therapy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
⨯
Daniel L. Comins,

Affiliation Department of Chemistry, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Howard L. McLeod

* E-mail: hmcleod@unc.edu

Affiliation Division of Pharmacotherapy and Experimental Therapeutics, Institute for Pharmacogenomics and Individualized Therapy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
⨯

Identification and Replication of Loci Involved in Camptothecin-Induced Cytotoxicity Using CEPH Pedigrees

Venita Gresham Watson,
Alison Motsinger-Reif,
Nicholas E. Hardison,
Eric J. Peters,
Tammy M. Havener,
Lorraine Everitt,
James Todd Auman,
Daniel L. Comins,
Howard L. McLeod

Published: May 5, 2011
https://doi.org/10.1371/journal.pone.0017561

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