TGF-β Inducible Early Gene 1 Regulates Osteoclast Differentiation and Survival by Mediating the NFATc1, AKT, and MEK/ERK Signaling Pathways

Open Access

Peer-reviewed

Research Article

Muzaffer Cicek ,

* E-mail: cicek.muzaffer@mayo.edu

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
⨯
Anne Vrabel,

Affiliation Endocrine Research Unit, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
⨯
Catherine Sturchio,

Affiliation Endocrine Research Unit, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
⨯
Larry Pederson,

Affiliation Endocrine Research Unit, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
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John R. Hawse,

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
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Malayannan Subramaniam,

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
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Thomas C. Spelsberg,

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
⨯
Merry Jo Oursler

Affiliations Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America, Endocrine Research Unit, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
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Osteoclasts
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Cell differentiation
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Bone marrow cells
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Precursor cells
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Apoptosis
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Osteoblast differentiation
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Gene expression
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Osteoblasts
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