Difluoromethylornithine Is a Novel Inhibitor of Helicobacter pylori Growth, CagA Translocation, and Interleukin-8 Induction

Daniel P. Barry; Mohammad Asim; David A. Leiman; Thibaut de Sablet; Kshipra Singh; Robert A. Casero Jr; Rupesh Chaturvedi; Keith T. Wilson

doi:10.1371/journal.pone.0017510

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Peer-reviewed

Research Article

Difluoromethylornithine Is a Novel Inhibitor of Helicobacter pylori Growth, CagA Translocation, and Interleukin-8 Induction

Daniel P. Barry,

Affiliations Division of Gastroenterology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America
⨯
Mohammad Asim,

Affiliations Division of Gastroenterology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America
⨯
David A. Leiman,

Affiliation Division of Gastroenterology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Thibaut de Sablet,

Affiliations Division of Gastroenterology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America
⨯
Kshipra Singh,

Affiliations Division of Gastroenterology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America
⨯
Robert A. Casero Jr,

Affiliation Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Rupesh Chaturvedi,

Affiliations Division of Gastroenterology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America
⨯
Keith T. Wilson

* E-mail: keith.wilson@vanderbilt.edu

Affiliations Division of Gastroenterology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America
⨯

Difluoromethylornithine Is a Novel Inhibitor of Helicobacter pylori Growth, CagA Translocation, and Interleukin-8 Induction

Daniel P. Barry,
Mohammad Asim,
David A. Leiman,
Thibaut de Sablet,
Kshipra Singh,
Robert A. Casero Jr,
Rupesh Chaturvedi,
Keith T. Wilson

Published: February 28, 2011
https://doi.org/10.1371/journal.pone.0017510

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