Sumoylation of Hypoxia-Inducible Factor-1α Ameliorates Failure of Brain Stem Cardiovascular Regulation in Experimental Brain Death

Julie Y. H. Chan; Ching-Yi Tsai; Carol H. Y. Wu; Faith C. H. Li; Kuang-Yu Dai; Enya Y. H. Sun; Samuel H. H. Chan; Alice Y. W. Chang

doi:10.1371/journal.pone.0017375

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Peer-reviewed

Research Article

Sumoylation of Hypoxia-Inducible Factor-1α Ameliorates Failure of Brain Stem Cardiovascular Regulation in Experimental Brain Death

Julie Y. H. Chan,

Affiliations Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, Republic of China, Center for Translational Research in Biomedical Sciences, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung, Taiwan, Republic of China
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Ching-Yi Tsai,

Affiliation Center for Translational Research in Biomedical Sciences, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung, Taiwan, Republic of China
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Carol H. Y. Wu,

Affiliation Center for Translational Research in Biomedical Sciences, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung, Taiwan, Republic of China
⨯
Faith C. H. Li,

Affiliation Center for Translational Research in Biomedical Sciences, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung, Taiwan, Republic of China
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Kuang-Yu Dai,

Affiliation Center for Translational Research in Biomedical Sciences, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung, Taiwan, Republic of China
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Enya Y. H. Sun,

Affiliation Center for Translational Research in Biomedical Sciences, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung, Taiwan, Republic of China
⨯
Samuel H. H. Chan ,

* E-mail: shhchan@adm.cgmh.org.tw (SHHC); cgmf.kmc@gmail.com (AYWC)

Affiliation Center for Translational Research in Biomedical Sciences, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung, Taiwan, Republic of China
⨯
Alice Y. W. Chang

* E-mail: shhchan@adm.cgmh.org.tw (SHHC); cgmf.kmc@gmail.com (AYWC)

Affiliation Center for Translational Research in Biomedical Sciences, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung, Taiwan, Republic of China
⨯

Sumoylation of Hypoxia-Inducible Factor-1α Ameliorates Failure of Brain Stem Cardiovascular Regulation in Experimental Brain Death

Julie Y. H. Chan,
Ching-Yi Tsai,
Carol H. Y. Wu,
Faith C. H. Li,
Kuang-Yu Dai,
Enya Y. H. Sun,
Samuel H. H. Chan,
Alice Y. W. Chang

Published: March 3, 2011
https://doi.org/10.1371/journal.pone.0017375

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