Maternal High Fat Diet Is Associated with Decreased Plasma n–3 Fatty Acids and Fetal Hepatic Apoptosis in Nonhuman Primates

Wilmon F. Grant; Melanie B. Gillingham; Ayesha K. Batra; Natasha M. Fewkes; Sarah M. Comstock; Diana Takahashi; Theodore P. Braun; Kevin L. Grove; Jacob E. Friedman; Daniel L. Marks

doi:10.1371/journal.pone.0017261

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Research Article

Maternal High Fat Diet Is Associated with Decreased Plasma n–3 Fatty Acids and Fetal Hepatic Apoptosis in Nonhuman Primates

Wilmon F. Grant,

Affiliations Neuroscience Graduate Program, Oregon Health & Science University, Portland, Oregon, United States of America, Department of Pediatrics, Oregon Health & Science University, Portland, Oregon, United States of America, Human Investigations Program of the Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, Oregon, United States of America
⨯
Melanie B. Gillingham,

Affiliation Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, Oregon, United States of America
⨯
Ayesha K. Batra,

Affiliation Center for the Study of Weight Regulation, Oregon Health & Science University, Portland, Oregon, United States of America
⨯
Natasha M. Fewkes,

Affiliation Department of Pediatrics, Oregon Health & Science University, Portland, Oregon, United States of America
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Sarah M. Comstock,

Affiliation Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America
⨯
Diana Takahashi,

Affiliation Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America
⨯
Theodore P. Braun,

Affiliation Department of Pediatrics, Oregon Health & Science University, Portland, Oregon, United States of America
⨯
Kevin L. Grove,

Affiliation Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America
⨯
Jacob E. Friedman,

Affiliation Department of Pediatrics, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Daniel L. Marks

* E-mail: marksd@ohsu.edu

Affiliations Neuroscience Graduate Program, Oregon Health & Science University, Portland, Oregon, United States of America, Department of Pediatrics, Oregon Health & Science University, Portland, Oregon, United States of America, Center for the Study of Weight Regulation, Oregon Health & Science University, Portland, Oregon, United States of America
⨯

Maternal High Fat Diet Is Associated with Decreased Plasma n–3 Fatty Acids and Fetal Hepatic Apoptosis in Nonhuman Primates

Wilmon F. Grant,
Melanie B. Gillingham,
Ayesha K. Batra,
Natasha M. Fewkes,
Sarah M. Comstock,
Diana Takahashi,
Theodore P. Braun,
Kevin L. Grove,
Jacob E. Friedman,
Daniel L. Marks

Published: February 25, 2011
https://doi.org/10.1371/journal.pone.0017261

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