Frequent and Simultaneous Epigenetic Inactivation of TP53 Pathway Genes in Acute Lymphoblastic Leukemia

• Amaia Vilas–Zornoza ,

  Contributed equally to this work with: Amaia Vilas–Zornoza, Xabier Agirre

  Affiliation Hematology Service and Area of Cell Therapy, Clínica Universidad de Navarra, Foundation for Applied Medical Research, University of Navarra, Pamplona, Spain

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• Xabier Agirre ,

  Contributed equally to this work with: Amaia Vilas–Zornoza, Xabier Agirre

  Affiliation Hematology Service and Area of Cell Therapy, Clínica Universidad de Navarra, Foundation for Applied Medical Research, University of Navarra, Pamplona, Spain

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• Vanesa Martín-Palanco,

  Affiliation Hematology Department, Reina Sofia Hospital, Maimonides Institute for Biomedical Research, Cordoba, Spain

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• José Ignacio Martín-Subero,

  Affiliation Department of Anatomic Pathology, Pharmacology and Microbiology, University of Barcelona, Barcelona, Spain

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• Edurne San José-Eneriz,

  Affiliation Hematology Service and Area of Cell Therapy, Clínica Universidad de Navarra, Foundation for Applied Medical Research, University of Navarra, Pamplona, Spain

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• Leire Garate,

  Affiliation Hematology Service and Area of Cell Therapy, Clínica Universidad de Navarra, Foundation for Applied Medical Research, University of Navarra, Pamplona, Spain

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• Sara Álvarez,

  Affiliation Molecular Cytogenetics Group, Centro Nacional Investigaciones Oncológicas (CNIO), Centro de Investigaciones de Enfermedades Raras (CIBERER), Madrid, Spain

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• Estíbaliz Miranda,

  Affiliation Hematology Service and Area of Cell Therapy, Clínica Universidad de Navarra, Foundation for Applied Medical Research, University of Navarra, Pamplona, Spain

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• Paula Rodríguez-Otero,

  Affiliation Hematology Service and Area of Cell Therapy, Clínica Universidad de Navarra, Foundation for Applied Medical Research, University of Navarra, Pamplona, Spain

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• José Rifón,

  Affiliation Hematology Service and Area of Cell Therapy, Clínica Universidad de Navarra, Foundation for Applied Medical Research, University of Navarra, Pamplona, Spain

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• Antonio Torres,

  Affiliation Hematology Department, Reina Sofia Hospital, Maimonides Institute for Biomedical Research, Cordoba, Spain

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• María José Calasanz,

  Affiliation Department of Genetics, University of Navarra, Navarra, Spain

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• Juan Cruz Cigudosa,

  Affiliation Molecular Cytogenetics Group, Centro Nacional Investigaciones Oncológicas (CNIO), Centro de Investigaciones de Enfermedades Raras (CIBERER), Madrid, Spain

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• José Román-Gómez ,

  ¶These authors also contributed equally to this work.

  Affiliation Hematology Department, Reina Sofia Hospital, Maimonides Institute for Biomedical Research, Cordoba, Spain

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• Felipe Prósper

  * E-mail: peperosa@teleline.es

  ¶These authors also contributed equally to this work.

  Affiliation Hematology Service and Area of Cell Therapy, Clínica Universidad de Navarra, Foundation for Applied Medical Research, University of Navarra, Pamplona, Spain

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