Localized Delivery of Interferon-β by Lactobacillus Exacerbates Experimental Colitis

Adelle P. McFarland; Ram Savan; Sagie Wagage; Augustina Addison; Karthika Ramakrishnan; Megan Karwan; Tri Duong; Howard A. Young

doi:10.1371/journal.pone.0016967

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Open Access

Peer-reviewed

Research Article

Localized Delivery of Interferon-β by Lactobacillus Exacerbates Experimental Colitis

Adelle P. McFarland,

Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯
Ram Savan,

Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯
Sagie Wagage,

Current address: Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯
Augustina Addison,

Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯
Karthika Ramakrishnan,

Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯
Megan Karwan,

Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯
Tri Duong,

Current address: Department of Poultry Science, Texas A&M University, College Station, Texas, United States of America

Affiliation Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Howard A. Young

* E-mail: YoungHow@mail.nih.gov

Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯

Localized Delivery of Interferon-β by Lactobacillus Exacerbates Experimental Colitis

Adelle P. McFarland,
Ram Savan,
Sagie Wagage,
Augustina Addison,
Karthika Ramakrishnan,
Megan Karwan,
Tri Duong,
Howard A. Young

Published: February 18, 2011
https://doi.org/10.1371/journal.pone.0016967

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Colitis
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Cytokines
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Colon
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Gastrointestinal tract
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Lactobacillus
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