IL-2 Suppression of IL-12p70 by a Recombinant HSV-1 Expressing IL-2 Induces T-Cell Auto-Reactivity and CNS Demyelination

Open Access

Peer-reviewed

Research Article

Mandana Zandian,

Affiliation Department of Surgery, Center for Neurobiology and Vaccine Development, Ophthalmology Research, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Kevin R. Mott,

Affiliation Department of Surgery, Center for Neurobiology and Vaccine Development, Ophthalmology Research, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Sariah J. Allen,

Affiliation Department of Surgery, Center for Neurobiology and Vaccine Development, Ophthalmology Research, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Shuang Chen,

Affiliation Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Moshe Arditi,

Affiliations Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, California, United States of America, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America
⨯
Homayon Ghiasi

* E-mail: ghiasih@cshs.org

Affiliation Department of Surgery, Center for Neurobiology and Vaccine Development, Ophthalmology Research, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯

Reader Comments (0)

T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Genetically modified animals
Is the Subject Area "Genetically modified animals" applicable to this article?

Thanks for your feedback.
Central nervous system
Is the Subject Area "Central nervous system" applicable to this article?

Thanks for your feedback.
Multiple sclerosis
Is the Subject Area "Multiple sclerosis" applicable to this article?

Thanks for your feedback.
Eye diseases
Is the Subject Area "Eye diseases" applicable to this article?

Thanks for your feedback.