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Open Access
Peer-reviewed
Research Article
Improved Innate and Adaptive Immunostimulation by Genetically Modified HIV-1 Protein Expressing NYVAC Vectors
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Esther D. Quakkelaar,
Affiliation Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
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Anke Redeker,
Affiliation Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
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Elias K. Haddad,
Current address: Vaccine and Gene Therapy Institute Florida, Port St. Lucie, Florida, United States of America
Affiliation Laboratoire d'Immunologie, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CR-CHUM), Montreal, Canada
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Alexandre Harari,
Affiliations Division of Immunology and Allergy, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, Swiss Vaccine Research Institute, Lausanne, Switzerland
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Stella Mayo McCaughey,
Affiliation Department of Medicine, University of Washington, Seattle, Washington, United States of America
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Thomas Duhen,
Affiliation Institute for Research in Biomedicine, Bellinzona, Switzerland
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Abdelali Filali-Mouhim,
Affiliation Laboratoire d'Immunologie, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CR-CHUM), Montreal, Canada
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Jean-Philippe Goulet,
Affiliation Laboratoire d'Immunologie, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CR-CHUM), Montreal, Canada
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Nikki M. Loof,
Affiliation Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
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Ferry Ossendorp,
Affiliation Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
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Beatriz Perdiguero,
Affiliation Centro Nacional de Biotecnologia, CSIC, Madrid, Spain
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Paul Heinen,
Affiliation Centro Nacional de Biotecnologia, CSIC, Madrid, Spain
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Carmen E. Gomez,
Affiliation Centro Nacional de Biotecnologia, CSIC, Madrid, Spain
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Karen V. Kibler,
Affiliation Arizona State University, Tempe, Arizona, United States of America
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David M. Koelle,
Affiliations Department of Medicine, University of Washington, Seattle, Washington, United States of America, Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Rafick P. Sékaly,
Current address: Vaccine and Gene Therapy Institute Florida, Port St. Lucie, Florida, United States of America
Affiliation Laboratoire d'Immunologie, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CR-CHUM), Montreal, Canada
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Federica Sallusto,
Affiliation Institute for Research in Biomedicine, Bellinzona, Switzerland
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Antonio Lanzavecchia,
Affiliation Institute for Research in Biomedicine, Bellinzona, Switzerland
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Giuseppe Pantaleo,
Affiliations Division of Immunology and Allergy, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, Swiss Vaccine Research Institute, Lausanne, Switzerland
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Mariano Esteban,
Affiliation Centro Nacional de Biotecnologia, CSIC, Madrid, Spain
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Jim Tartaglia,
Affiliation Sanofi Pasteur, Swiftwater, Pennsylvania, United States of America
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Bertram L. Jacobs,
Affiliation Arizona State University, Tempe, Arizona, United States of America
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Cornelis J. M. Melief
* E-mail: c.melief@lumc.nl
Affiliations Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands, ISA Pharmaceuticals B.V., Bilthoven, The Netherlands
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Improved Innate and Adaptive Immunostimulation by Genetically Modified HIV-1 Protein Expressing NYVAC Vectors
- Esther D. Quakkelaar,
- Anke Redeker,
- Elias K. Haddad,
- Alexandre Harari,
- Stella Mayo McCaughey,
- Thomas Duhen,
- Abdelali Filali-Mouhim,
- Jean-Philippe Goulet,
- Nikki M. Loof,
- Ferry Ossendorp
- Published: February 15, 2011
- https://doi.org/10.1371/journal.pone.0016819