Chemogenomic Analysis of G-Protein Coupled Receptors and Their Ligands Deciphers Locks and Keys Governing Diverse Aspects of Signalling

Open Access

Peer-reviewed

Research Article

Jörg D. Wichard,

Affiliations Leibniz-Institut für Molekulare Pharmakologie, Berlin, Germany, Bayer-Schering Pharma, Berlin, Germany
⨯
Antonius ter Laak,

Affiliation Bayer-Schering Pharma, Berlin, Germany
⨯
Gerd Krause,

Affiliation Leibniz-Institut für Molekulare Pharmakologie, Berlin, Germany
⨯
Nikolaus Heinrich,

Affiliation Bayer-Schering Pharma, Berlin, Germany
⨯
Ronald Kühne ,

* E-mail: kuehne@fmp-berlin.de

Affiliation Leibniz-Institut für Molekulare Pharmakologie, Berlin, Germany
⨯
Gunnar Kleinau

Affiliations Leibniz-Institut für Molekulare Pharmakologie, Berlin, Germany, Institute of Experimental Pediatric Endocrinology, Charité Universitätsmedizin Berlin, Berlin, Germany
⨯

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G protein coupled receptors
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G-protein signaling
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Transmembrane receptors
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Amino acid analysis
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Crystal structure
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Intracellular receptors
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Membrane receptor signaling
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Signal transduction
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