A PXR-Mediated Negative Feedback Loop Attenuates the Expression of CYP3A in Response to the PXR Agonist Pregnenalone-16α-Carbonitrile

Open Access

Peer-reviewed

Research Article

Ian Bailey,

Affiliation Faculty of Health and Medical Sciences, Centre for Toxicology, University of Surrey, Surrey, United Kingdom
⨯
G. Gordon Gibson,

Affiliation Faculty of Health and Medical Sciences, Centre for Toxicology, University of Surrey, Surrey, United Kingdom
⨯
Kathryn Plant,

Affiliation Faculty of Health and Medical Sciences, Centre for Toxicology, University of Surrey, Surrey, United Kingdom
⨯
Mark Graham,

Affiliation Safety Assessment, AstraZeneca R&D Charnwood, Leicester, United Kingdom
⨯
Nick Plant

* E-mail: N.Plant@Surrey.ac.uk

Affiliation Faculty of Health and Medical Sciences, Centre for Toxicology, University of Surrey, Surrey, United Kingdom
⨯

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