An Effective Assessment of Simvastatin-Induced Toxicity with NMR-Based Metabonomics Approach

Hye-ji Yang; Myung-Joo Choi; He Wen; Hyuk Nam Kwon; Kyung Hee Jung; Sang-Won Hong; Joon Mee Kim; Soon-Sun Hong; Sunghyouk Park

doi:10.1371/journal.pone.0016641

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Open Access

Peer-reviewed

Research Article

An Effective Assessment of Simvastatin-Induced Toxicity with NMR-Based Metabonomics Approach

Hye-ji Yang ,

Contributed equally to this work with: Hye-ji Yang, Myung-Joo Choi, He Wen

Affiliation Department of Biochemistry, Inha University Hospital and Center for Advanced Medical Education by BK21 project, College of Medicine, Inha University, Incheon, Korea
⨯
Myung-Joo Choi ,

Contributed equally to this work with: Hye-ji Yang, Myung-Joo Choi, He Wen

Affiliation Department of Biomedical Sciences, Inha University Hospital and Center for Advanced Medical Education by BK21 project, College of Medicine, Inha University, Incheon, Korea
⨯
He Wen ,

Contributed equally to this work with: Hye-ji Yang, Myung-Joo Choi, He Wen

Affiliation Department of Biochemistry, Inha University Hospital and Center for Advanced Medical Education by BK21 project, College of Medicine, Inha University, Incheon, Korea
⨯
Hyuk Nam Kwon,

Affiliation Department of Biochemistry, Inha University Hospital and Center for Advanced Medical Education by BK21 project, College of Medicine, Inha University, Incheon, Korea
⨯
Kyung Hee Jung,

Affiliation Department of Biomedical Sciences, Inha University Hospital and Center for Advanced Medical Education by BK21 project, College of Medicine, Inha University, Incheon, Korea
⨯
Sang-Won Hong,

Affiliation Department of Biomedical Sciences, Inha University Hospital and Center for Advanced Medical Education by BK21 project, College of Medicine, Inha University, Incheon, Korea
⨯
Joon Mee Kim,

Affiliation Department of Pathology, Inha University Hospital and Center for Advanced Medical Education by BK21 project, College of Medicine, Inha University, Incheon, Korea
⨯
Soon-Sun Hong ,

* E-mail: spark@inha.ac.kr (SP); hongs@inha.ac.kr (S-SH)

Affiliation Department of Biomedical Sciences, Inha University Hospital and Center for Advanced Medical Education by BK21 project, College of Medicine, Inha University, Incheon, Korea
⨯
Sunghyouk Park

* E-mail: spark@inha.ac.kr (SP); hongs@inha.ac.kr (S-SH)

Affiliation Department of Biochemistry, Inha University Hospital and Center for Advanced Medical Education by BK21 project, College of Medicine, Inha University, Incheon, Korea
⨯

An Effective Assessment of Simvastatin-Induced Toxicity with NMR-Based Metabonomics Approach

Hye-ji Yang,
Myung-Joo Choi,
He Wen,
Hyuk Nam Kwon,
Kyung Hee Jung,
Sang-Won Hong,
Joon Mee Kim,
Soon-Sun Hong,
Sunghyouk Park

Published: February 22, 2011
https://doi.org/10.1371/journal.pone.0016641

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