Reduced Stability and Increased Dynamics in the Human Proliferating Cell Nuclear Antigen (PCNA) Relative to the Yeast Homolog

Open Access

Peer-reviewed

Research Article

Alfredo De Biasio,

Affiliation Structural Biology Unit, CIC bioGUNE, Derio, Spain
⨯
Ricardo Sánchez,

Affiliation Structural Biology Unit, CIC bioGUNE, Derio, Spain
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Jesús Prieto,

Affiliation Structural and Computational Biology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain
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Maider Villate,

Affiliation Structural Biology Unit, CIC bioGUNE, Derio, Spain
⨯
Ramón Campos-Olivas,

Affiliation Structural and Computational Biology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain
⨯
Francisco J. Blanco

* E-mail: fblanco@cicbiogune.es

Affiliations Structural Biology Unit, CIC bioGUNE, Derio, Spain, IKERBASQUE, Basque Foundation for Science, Bilbao, Spain
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Urea
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Yeast
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Free energy
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Monomers
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Crystal structure
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Denaturation
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DNA clamps
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Protein denaturation
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