Peripheral Delivery of a CNS Targeted, Metalo-Protease Reduces Aβ Toxicity in a Mouse Model of Alzheimer's Disease

• Brian Spencer,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Robert A. Marr,

  Affiliation Department of Neuroscience, Center for Stem Cell and Regenerative Medicine, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America

  ⨯
• Ryan Gindi,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Rewati Potkar,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Sarah Michael,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Anthony Adame,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Edward Rockenstein,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Inder M. Verma,

  Affiliation Laboratory of Genetics, Salk Institute for Biological Studies, San Diego, California, United States of America

  ⨯
• Eliezer Masliah

  * E-mail: emasliah@ucsd.edu

  Affiliations Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America, Department of Pathology, University of California San Diego, La Jolla, California, United States of America

  ⨯