Intracellular S1P Generation Is Essential for S1P-Induced Motility of Human Lung Endothelial Cells: Role of Sphingosine Kinase 1 and S1P Lyase

• Evgeny V. Berdyshev,

  Affiliations Department of Medicine, The University of Illinois at Chicago, Chicago, Illinois, United States of America, Institute for Personalized Respiratory Medicine, The University of Illinois at Chicago, Chicago, Illinois, United States of America

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• Irina Gorshkova,

  Affiliations Department of Medicine, The University of Illinois at Chicago, Chicago, Illinois, United States of America, Institute for Personalized Respiratory Medicine, The University of Illinois at Chicago, Chicago, Illinois, United States of America

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• Peter Usatyuk,

  Affiliations Department of Pharmacology, The University of Illinois at Chicago, Chicago, Illinois, United States of America, Institute for Personalized Respiratory Medicine, The University of Illinois at Chicago, Chicago, Illinois, United States of America

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• Satish Kalari,

  Affiliation Department of Cancer Biology, Beckman Research Institute, Duarte, California, United States of America

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• Yutong Zhao,

  Affiliation Department of Medicine, University of Pittsburgh Medical Center, Pittsburg, Pennsylvania, United States of America

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• Nigel J. Pyne,

  Affiliation Cell Biology Group, University of Strathclyde, Glasgow, United Kingdom

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• Susan Pyne,

  Affiliation Cell Biology Group, University of Strathclyde, Glasgow, United Kingdom

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• Roger A. Sabbadini,

  Affiliation Department of Biology, San Diego State University, and Lpath Inc., San Diego, California, United States of America

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• Joe G. N. Garcia,

  Affiliations Department of Medicine, The University of Illinois at Chicago, Chicago, Illinois, United States of America, Institute for Personalized Respiratory Medicine, The University of Illinois at Chicago, Chicago, Illinois, United States of America

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• Viswanathan Natarajan

  * E-mail: visnatar@uic.edu

  Affiliations Department of Medicine, The University of Illinois at Chicago, Chicago, Illinois, United States of America, Department of Pharmacology, The University of Illinois at Chicago, Chicago, Illinois, United States of America, Institute for Personalized Respiratory Medicine, The University of Illinois at Chicago, Chicago, Illinois, United States of America

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