The N–Terminal Tail of hERG Contains an Amphipathic α–Helix That Regulates Channel Deactivation

• Chai Ann Ng ,

  Contributed equally to this work with: Chai Ann Ng, Mark J. Hunter, Matthew D. Perry

  Affiliations Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia, School of Molecular Biosciences, University of Sydney, Sydney, New South Wales, Australia

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• Mark J. Hunter ,

  Contributed equally to this work with: Chai Ann Ng, Mark J. Hunter, Matthew D. Perry

  Affiliation Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia

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• Matthew D. Perry ,

  Contributed equally to this work with: Chai Ann Ng, Mark J. Hunter, Matthew D. Perry

  Affiliation Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia

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• Mehdi Mobli,

  Affiliation Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia

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• Ying Ke,

  Affiliation Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia

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• Philip W. Kuchel,

  Affiliation School of Molecular Biosciences, University of Sydney, Sydney, New South Wales, Australia

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• Glenn F. King,

  Affiliation Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia

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• Daniela Stock,

  Affiliations Structural and Computational Biology Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia, St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales, Australia

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• Jamie I. Vandenberg

  * E-mail: j.vandenberg@victorchang.edu.au

  Affiliations Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia, School of Molecular Biosciences, University of Sydney, Sydney, New South Wales, Australia, St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales, Australia

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