Re-Evaluation of the Action Potential Upstroke Velocity as a Measure of the Na+ Current in Cardiac Myocytes at Physiological Conditions

Open Access

Peer-reviewed

Research Article

Re-Evaluation of the Action Potential Upstroke Velocity as a Measure of the Na⁺ Current in Cardiac Myocytes at Physiological Conditions

Géza Berecki,

Affiliation Department of Anatomy, Embryology, and Physiology, Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Ronald Wilders,

Affiliation Department of Anatomy, Embryology, and Physiology, Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Berend de Jonge,

Affiliation Department of Anatomy, Embryology, and Physiology, Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Antoni C. G. van Ginneken,

Affiliation Department of Anatomy, Embryology, and Physiology, Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Arie O. Verkerk

* E-mail: A.O.Verkerk@amc.uva.nl

Affiliation Department of Anatomy, Embryology, and Physiology, Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Muscle cells
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Membrane potential
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HEK 293 cells
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Action potentials
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Heart failure
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Biophysics
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Rabbits
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Patch clamp techniques
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