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Open Access

Peer-reviewed

Research Article

Tailoring Adjuvant Endocrine Therapy for Postmenopausal Breast Cancer: A CYP2D6 Multiple-Genotype-Based Modeling Analysis and Validation

Ke-Da Yu ,

Contributed equally to this work with: Ke-Da Yu, A-Ji Huang

Affiliation Department of Oncology, Shanghai Medical College, Cancer Institute and Cancer Center, Institutes of Biomedical Science, Fudan University, Shanghai, People's Republic of China
⨯
A-Ji Huang ,

Contributed equally to this work with: Ke-Da Yu, A-Ji Huang

Affiliation Department of Oncology, Shanghai Medical College, Cancer Institute and Cancer Center, Institutes of Biomedical Science, Fudan University, Shanghai, People's Republic of China
⨯
Zhi-Ming Shao

* E-mail: zhimingshao@yahoo.com

Affiliation Department of Oncology, Shanghai Medical College, Cancer Institute and Cancer Center, Institutes of Biomedical Science, Fudan University, Shanghai, People's Republic of China
⨯

Tailoring Adjuvant Endocrine Therapy for Postmenopausal Breast Cancer: A CYP2D6 Multiple-Genotype-Based Modeling Analysis and Validation

Ke-Da Yu,
A-Ji Huang,
Zhi-Ming Shao

x

Published: December 20, 2010
https://doi.org/10.1371/journal.pone.0015649

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Breast cancer
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Endocrine therapy
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Alleles
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Enzyme metabolism
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Homozygosity
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Cancer treatment
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