Gene Expression Profiling Reveals New Aspects of PIK3CA Mutation in ERalpha-Positive Breast Cancer: Major Implication of the Wnt Signaling Pathway

Magdalena Cizkova; Géraldine Cizeron-Clairac; Sophie Vacher; Aurélie Susini; Catherine Andrieu; Rosette Lidereau; Ivan Bièche

doi:10.1371/journal.pone.0015647

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Research Article

Gene Expression Profiling Reveals New Aspects of PIK3CA Mutation in ERalpha-Positive Breast Cancer: Major Implication of the Wnt Signaling Pathway

Magdalena Cizkova ,

Contributed equally to this work with: Magdalena Cizkova, Géraldine Cizeron-Clairac

Affiliations Laboratoire d'Oncogénétique, Institut National de la Santé et de la Recherche, U745, Institut Curie/Hôpital René Huguenin, St-Cloud, France, Laboratory of Experimental Medicine, Department of Paediatrics, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Olomouc, Czech Republic
⨯
Géraldine Cizeron-Clairac ,

Contributed equally to this work with: Magdalena Cizkova, Géraldine Cizeron-Clairac

Affiliation Laboratoire d'Oncogénétique, Institut National de la Santé et de la Recherche, U745, Institut Curie/Hôpital René Huguenin, St-Cloud, France
⨯
Sophie Vacher,

Affiliation Laboratoire d'Oncogénétique, Institut National de la Santé et de la Recherche, U745, Institut Curie/Hôpital René Huguenin, St-Cloud, France
⨯
Aurélie Susini,

Affiliation Laboratoire d'Oncogénétique, Institut National de la Santé et de la Recherche, U745, Institut Curie/Hôpital René Huguenin, St-Cloud, France
⨯
Catherine Andrieu,

Affiliation Laboratoire d'Oncogénétique, Institut National de la Santé et de la Recherche, U745, Institut Curie/Hôpital René Huguenin, St-Cloud, France
⨯
Rosette Lidereau,

Affiliation Laboratoire d'Oncogénétique, Institut National de la Santé et de la Recherche, U745, Institut Curie/Hôpital René Huguenin, St-Cloud, France
⨯
Ivan Bièche

* E-mail: i.bieche@stcloud-huguenin.org

Affiliation Laboratoire d'Oncogénétique, Institut National de la Santé et de la Recherche, U745, Institut Curie/Hôpital René Huguenin, St-Cloud, France
⨯

Gene Expression Profiling Reveals New Aspects of PIK3CA Mutation in ERalpha-Positive Breast Cancer: Major Implication of the Wnt Signaling Pathway

Magdalena Cizkova,
Géraldine Cizeron-Clairac,
Sophie Vacher,
Aurélie Susini,
Catherine Andrieu,
Rosette Lidereau,
Ivan Bièche

Published: December 30, 2010
https://doi.org/10.1371/journal.pone.0015647

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Breast cancer
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Breast tumors
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Gene expression
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Mutation
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Wnt signaling cascade
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Reverse transcriptase-polymerase chain reaction
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Gene regulation
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Microarrays
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