Enumeration of Functional T-Cell Subsets by Fluorescence-Immunospot Defines Signatures of Pathogen Burden in Tuberculosis

Rosalyn Casey; Deena Blumenkrantz; Kerry Millington; Damien Montamat-Sicotte; Onn Min Kon; Melissa Wickremasinghe; Samuel Bremang; Murphy Magtoto; Saranya Sridhar; David Connell; Ajit Lalvani

doi:10.1371/journal.pone.0015619

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Research Article

Enumeration of Functional T-Cell Subsets by Fluorescence-Immunospot Defines Signatures of Pathogen Burden in Tuberculosis

Rosalyn Casey,

Affiliation Tuberculosis Research Unit, Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Deena Blumenkrantz ,

Contributed equally to this work with: Deena Blumenkrantz, Kerry Millington

Affiliation Tuberculosis Research Unit, Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Kerry Millington ,

Contributed equally to this work with: Deena Blumenkrantz, Kerry Millington

Current address: Liverpool School of Tropical Medicine, Liverpool, United Kingdom

Affiliation Tuberculosis Research Unit, Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Damien Montamat-Sicotte,

Affiliation Tuberculosis Research Unit, Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Onn Min Kon,

Affiliation Imperial College Healthcare NHS Trust, St Mary's Hospital, London, United Kingdom
⨯
Melissa Wickremasinghe,

Affiliation Imperial College Healthcare NHS Trust, St Mary's Hospital, London, United Kingdom
⨯
Samuel Bremang,

Affiliation Tuberculosis Research Unit, Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Murphy Magtoto,

Affiliation Tuberculosis Research Unit, Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Saranya Sridhar,

Affiliation Tuberculosis Research Unit, Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
David Connell,

Affiliation Tuberculosis Research Unit, Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Ajit Lalvani

* E-mail: a.lalvani@imperial.ac.uk

Affiliation Tuberculosis Research Unit, Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯

Enumeration of Functional T-Cell Subsets by Fluorescence-Immunospot Defines Signatures of Pathogen Burden in Tuberculosis

Rosalyn Casey,
Deena Blumenkrantz,
Kerry Millington,
Damien Montamat-Sicotte,
Onn Min Kon,
Melissa Wickremasinghe,
Samuel Bremang,
Murphy Magtoto,
Saranya Sridhar,
David Connell

Published: December 14, 2010
https://doi.org/10.1371/journal.pone.0015619

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