A Novel Statistical Algorithm for Gene Expression Analysis Helps Differentiate Pregnane X Receptor-Dependent and Independent Mechanisms of Toxicity

• M. Ann Mongan ,

  * E-mail: thuyv@amgen.com

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Robert T. Dunn II,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Steven Vonderfecht,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Nancy Everds,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Guang Chen,

  Affiliation Research and Translational Sciences Biostatistics, Amgen Inc., Seattle, Washington, United States of America

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• Cheng Su,

  Affiliation Research and Translational Sciences Biostatistics, Amgen Inc., Seattle, Washington, United States of America

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• Marnie Higgins-Garn,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Yuan Chen,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Cynthia A. Afshari,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Toni L. Williamson,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Linda Carlock,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Christopher DiPalma,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Suzanne Moss,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Jeanine Bussiere,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Charles Qualls Jr.,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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• Yudong D. He,

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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•  [ ... ],
• Hisham K. Hamadeh

  Affiliation Comparative Biology and Safety Sciences, Amgen Inc., Thousand Oaks, California, United States of America

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