Pyrvinium, a Potent Small Molecule Wnt Inhibitor, Promotes Wound Repair and Post-MI Cardiac Remodeling

Open Access

Peer-reviewed

Research Article

Sarika Saraswati,

Affiliation Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Maria P. Alfaro,

Affiliation Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Curtis A. Thorne,

Affiliation Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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James Atkinson,

Affiliations Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, The Department of Veterans Affairs Medical Center, Nashville, Tennessee, United States of America
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Ethan Lee,

Affiliation Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Pampee P. Young

* E-mail: pampee.young@vanderbilt.edu

Affiliations Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, The Department of Veterans Affairs Medical Center, Nashville, Tennessee, United States of America, Department of Internal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Wnt signaling cascade
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Signal inhibition
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Cardiomyocytes
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Granulation tissue
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Myocardial infarction
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Myocardium
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Apoptosis
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HEK 293 cells
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