Surface Phenotype and Functionality of WNV Specific T Cells Differ with Age and Disease Severity

Paolo Piazza; Curtis P. McMurtrey; Alina Lelic; Robert L. Cook; Rachel Hess; Eric Yablonsky; Luann Borowski; Mark B. Loeb; Jonathan L. Bramson; William H. Hildebrand; Charles R. Rinaldo

doi:10.1371/journal.pone.0015343

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Open Access

Peer-reviewed

Research Article

Surface Phenotype and Functionality of WNV Specific T Cells Differ with Age and Disease Severity

Paolo Piazza ,

Contributed equally to this work with: Paolo Piazza, Curtis P. McMurtrey

Affiliation Department of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, United States of America
⨯
Curtis P. McMurtrey ,

Contributed equally to this work with: Paolo Piazza, Curtis P. McMurtrey

Affiliation Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
⨯
Alina Lelic,

Affiliation Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Robert L. Cook,

Affiliation Department of Epidemiology and Biostatistics, University of Florida Health Sciences Center, Gainesville, Florida, United States of America
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Rachel Hess,

Affiliation Center for Research on Health Care, Pittsburgh, Pennsylvania, United States of America
⨯
Eric Yablonsky,

Affiliation Department of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, United States of America
⨯
Luann Borowski,

Affiliation Department of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, United States of America
⨯
Mark B. Loeb,

Affiliation Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Jonathan L. Bramson,

Affiliation Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
William H. Hildebrand ,

* E-mail: William-hildebrand@ouhsc.edu

Affiliation Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
⨯
Charles R. Rinaldo

Affiliation Department of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, United States of America
⨯

Surface Phenotype and Functionality of WNV Specific T Cells Differ with Age and Disease Severity

Paolo Piazza,
Curtis P. McMurtrey,
Alina Lelic,
Robert L. Cook,
Rachel Hess,
Eric Yablonsky,
Luann Borowski,
Mark B. Loeb,
Jonathan L. Bramson,
William H. Hildebrand

Published: December 13, 2010
https://doi.org/10.1371/journal.pone.0015343

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