Coxiella burnetii, the Agent of Q Fever, Replicates within Trophoblasts and Induces a Unique Transcriptional Response

Amira Ben Amara; Eric Ghigo; Yannick Le Priol; Catherine Lépolard; Suzana P. Salcedo; Emmanuel Lemichez; Florence Bretelle; Christian Capo; Jean-Louis Mege

doi:10.1371/journal.pone.0015315

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Peer-reviewed

Research Article

Coxiella burnetii, the Agent of Q Fever, Replicates within Trophoblasts and Induces a Unique Transcriptional Response

Amira Ben Amara,

Affiliation Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes, CNRS-IRD UMR 6236, IFR 48, Université de la Méditerranée, Marseille, France
⨯
Eric Ghigo,

Affiliation Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes, CNRS-IRD UMR 6236, IFR 48, Université de la Méditerranée, Marseille, France
⨯
Yannick Le Priol,

Affiliation IMTSSA, Transcriptomic Platform, Parc du Pharo, Marseille, France
⨯
Catherine Lépolard,

Affiliation Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes, CNRS-IRD UMR 6236, IFR 48, Université de la Méditerranée, Marseille, France
⨯
Suzana P. Salcedo,

Affiliation Centre d'Immunologie de Marseille-Luminy, Université de la Méditerranée, UMR 6546, Marseille, France
⨯
Emmanuel Lemichez,

Affiliation INSERM Unité 895, Equipe 6, C3M, Microbial Toxins in Host Pathogen Interactions, Nice, France
⨯
Florence Bretelle,

Affiliation Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes, CNRS-IRD UMR 6236, IFR 48, Université de la Méditerranée, Marseille, France
⨯
Christian Capo,

Affiliation Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes, CNRS-IRD UMR 6236, IFR 48, Université de la Méditerranée, Marseille, France
⨯
Jean-Louis Mege

* E-mail: Jean-Louis.Mege@univmed.fr

Affiliation Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes, CNRS-IRD UMR 6236, IFR 48, Université de la Méditerranée, Marseille, France
⨯

Coxiella burnetii, the Agent of Q Fever, Replicates within Trophoblasts and Induces a Unique Transcriptional Response

Amira Ben Amara,
Eric Ghigo,
Yannick Le Priol,
Catherine Lépolard,
Suzana P. Salcedo,
Emmanuel Lemichez,
Florence Bretelle,
Christian Capo,
Jean-Louis Mege

Published: December 14, 2010
https://doi.org/10.1371/journal.pone.0015315

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Coxiella burnetii
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Trophoblasts
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Inflammation
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Cytokines
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Apoptosis
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Macrophages
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Placenta
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Pregnancy
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