A Novel Mutation in the Maternally Imprinted PEG3 Domain Results in a Loss of MIMT1 Expression and Causes Abortions and Stillbirths in Cattle (Bos taurus)

Krzysztof Flisikowski; Heli Venhoranta; Joanna Nowacka-Woszuk; Stephanie D. McKay; Antti Flyckt; Juhani Taponen; Robert Schnabel; Hermann Schwarzenbacher; Izabela Szczerbal; Hannes Lohi; Ruedi Fries; Jeremy F. Taylor; Marek Switonski; Magnus Andersson

doi:10.1371/journal.pone.0015116

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Peer-reviewed

Research Article

A Novel Mutation in the Maternally Imprinted PEG3 Domain Results in a Loss of MIMT1 Expression and Causes Abortions and Stillbirths in Cattle (Bos taurus)

Krzysztof Flisikowski ,

* E-mail: flisikowski@wzw.tum.de

Current address: Lehrstuhl für Biotechnologie der Nutztiere, Technische Universität Munchen, Freising, Germany

Affiliation Lehrstuhl für Tierzucht, Technische Universitaet Munchen, Freising, Germany
⨯
Heli Venhoranta,

Affiliation Department of Production Animal Medicine, University of Helsinki, Saarentaus, Finland
⨯
Joanna Nowacka-Woszuk,

Affiliation Department of Genetics and Animal Breeding, University of Life Sciences, Poznan, Poland
⨯
Stephanie D. McKay,

Affiliation Division of Animal Sciences, University of Missouri, Columbia, Missouri, United States of America
⨯
Antti Flyckt,

Affiliation Department of Production Animal Medicine, University of Helsinki, Saarentaus, Finland
⨯
Juhani Taponen,

Affiliation Department of Production Animal Medicine, University of Helsinki, Saarentaus, Finland
⨯
Robert Schnabel,

Affiliation Division of Animal Sciences, University of Missouri, Columbia, Missouri, United States of America
⨯
Hermann Schwarzenbacher,

Affiliations Lehrstuhl für Tierzucht, Technische Universitaet Munchen, Freising, Germany, ZuchtData, EDV-Dienstleistungen GmbH, Wien, Austria
⨯
Izabela Szczerbal,

Affiliation Department of Genetics and Animal Breeding, University of Life Sciences, Poznan, Poland
⨯
Hannes Lohi,

Affiliation Program in Molecular Medicine, Veterinary Biosciences, Department of Medical Genetics, Folkhälsan Institute of Genetics, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
⨯
Ruedi Fries,

Affiliation Lehrstuhl für Tierzucht, Technische Universitaet Munchen, Freising, Germany
⨯
Jeremy F. Taylor,

Affiliation Division of Animal Sciences, University of Missouri, Columbia, Missouri, United States of America
⨯
Marek Switonski,

Affiliation Department of Genetics and Animal Breeding, University of Life Sciences, Poznan, Poland
⨯
Magnus Andersson

Affiliation Department of Production Animal Medicine, University of Helsinki, Saarentaus, Finland
⨯

A Novel Mutation in the Maternally Imprinted PEG3 Domain Results in a Loss of MIMT1 Expression and Causes Abortions and Stillbirths in Cattle (Bos taurus)

Krzysztof Flisikowski,
Heli Venhoranta,
Joanna Nowacka-Woszuk,
Stephanie D. McKay,
Antti Flyckt,
Juhani Taponen,
Robert Schnabel,
Hermann Schwarzenbacher,
Izabela Szczerbal,
Hannes Lohi

Published: November 30, 2010
https://doi.org/10.1371/journal.pone.0015116

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Single nucleotide polymorphisms
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