Synaptic Protection in the Brain of WldS Mice Occurs Independently of Age but Is Sensitive to Gene-Dose

Open Access

Peer-reviewed

Research Article

Synaptic Protection in the Brain of Wld^S Mice Occurs Independently of Age but Is Sensitive to Gene-Dose

Ann K. Wright,

Affiliations Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom
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Thomas M. Wishart,

Affiliations Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom
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Cali A. Ingham,

Affiliation Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom
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Thomas H. Gillingwater

* E-mail: T.Gillingwater@ed.ac.uk

Affiliations Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom
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Synapses
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Homozygosity
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Heterozygosity
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Neostriatum
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Central nervous system
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Aging
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Mouse models
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Gene expression
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