VKORC1 Pharmacogenetics and Pharmacoproteomics in Patients on Warfarin Anticoagulant Therapy: Transthyretin Precursor as a Potential Biomarker

Ramasamy Saminathan; Jing Bai; Laleh Sadrolodabaee; Govindasamy Muralidharan Karthik; Onkar Singh; Koilan Subramaniyan; Chi Bun Ching; Wei Ning Chen; Balram Chowbay

doi:10.1371/journal.pone.0015064

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Peer-reviewed

Research Article

VKORC1 Pharmacogenetics and Pharmacoproteomics in Patients on Warfarin Anticoagulant Therapy: Transthyretin Precursor as a Potential Biomarker

Ramasamy Saminathan ,

Contributed equally to this work with: Ramasamy Saminathan, Jing Bai, Laleh Sadrolodabaee

Affiliation Laboratory of Clinical Pharmacology, Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore, Singapore
⨯
Jing Bai ,

Contributed equally to this work with: Ramasamy Saminathan, Jing Bai, Laleh Sadrolodabaee

Affiliation School of Chemical and Biomedical Engineering, College of Engineering, Nanyang Technological University, Singapore, Singapore
⨯
Laleh Sadrolodabaee ,

Contributed equally to this work with: Ramasamy Saminathan, Jing Bai, Laleh Sadrolodabaee

Affiliation School of Chemical and Biomedical Engineering, College of Engineering, Nanyang Technological University, Singapore, Singapore
⨯
Govindasamy Muralidharan Karthik,

Affiliation Laboratory of Clinical Pharmacology, Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore, Singapore
⨯
Onkar Singh,

Affiliation Laboratory of Clinical Pharmacology, Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore, Singapore
⨯
Koilan Subramaniyan,

Affiliation Laboratory of Clinical Pharmacology, Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore, Singapore
⨯
Chi Bun Ching,

Affiliation School of Chemical and Biomedical Engineering, College of Engineering, Nanyang Technological University, Singapore, Singapore
⨯
Wei Ning Chen ,

* E-mail: ctebal@nccs.com.sg (BC); WNChen@ntu.edu.sg (WNC)

Affiliation School of Chemical and Biomedical Engineering, College of Engineering, Nanyang Technological University, Singapore, Singapore
⨯
Balram Chowbay

* E-mail: ctebal@nccs.com.sg (BC); WNChen@ntu.edu.sg (WNC)

Affiliation Laboratory of Clinical Pharmacology, Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore, Singapore
⨯

VKORC1 Pharmacogenetics and Pharmacoproteomics in Patients on Warfarin Anticoagulant Therapy: Transthyretin Precursor as a Potential Biomarker

Ramasamy Saminathan,
Jing Bai,
Laleh Sadrolodabaee,
Govindasamy Muralidharan Karthik,
Onkar Singh,
Koilan Subramaniyan,
Chi Bun Ching,
Wei Ning Chen,
Balram Chowbay

Published: December 13, 2010
https://doi.org/10.1371/journal.pone.0015064

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Pharmacogenetics
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Protein expression
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Biomarkers
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Thyroid hormones
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Anticoagulant therapy
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Gene expression
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Proteomics
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Plasma proteins
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