Reactive Oxygen Species Production and Mitochondrial Dysfunction Contribute to Quercetin Induced Death in Leishmania amazonensis

Open Access

Peer-reviewed

Research Article

Fernanda Fonseca-Silva,

Affiliation Laboratório de Bioquímica de Tripanosomatideos, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Rio de Janeiro, Brazil
⨯
Job D. F. Inacio,

Affiliation Laboratório de Bioquímica de Tripanosomatideos, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Rio de Janeiro, Brazil
⨯
Marilene M. Canto-Cavalheiro,

Affiliation Laboratório de Bioquímica de Tripanosomatideos, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Rio de Janeiro, Brazil
⨯
Elmo Eduardo Almeida-Amaral

* E-mail: elmo@ioc.fiocruz.br

Affiliation Laboratório de Bioquímica de Tripanosomatideos, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Rio de Janeiro, Brazil
⨯

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Promastigotes
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Mitochondria
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Leishmania
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Glutathione
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Membrane potential
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Mitochondrial membrane
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Reactive oxygen species
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Drosophila melanogaster
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