Two-Component System RgfA/C Activates the fbsB Gene Encoding Major Fibrinogen-Binding Protein in Highly Virulent CC17 Clone Group B Streptococcus

Rim Al Safadi; Laurent Mereghetti; Mazen Salloum; Marie-Frédérique Lartigue; Isabelle Virlogeux-Payant; Roland Quentin; Agnès Rosenau

doi:10.1371/journal.pone.0014658

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Peer-reviewed

Research Article

Two-Component System RgfA/C Activates the fbsB Gene Encoding Major Fibrinogen-Binding Protein in Highly Virulent CC17 Clone Group B Streptococcus

Rim Al Safadi,

Affiliation Equipe d'Accueil 3854 Bactéries et risque materno-fœtal, Institut Fédératif de Recherche 136 Agents Transmissibles et Infectiologie, UFR Médecine, Université François Rabelais de Tours, Tours, France
⨯
Laurent Mereghetti,

Affiliations Equipe d'Accueil 3854 Bactéries et risque materno-fœtal, Institut Fédératif de Recherche 136 Agents Transmissibles et Infectiologie, UFR Médecine, Université François Rabelais de Tours, Tours, France, Service de Bactériologie-Virologie, Hôpital Bretonneau, CHRU de Tours, Tours, France
⨯
Mazen Salloum,

Affiliation Equipe d'Accueil 3854 Bactéries et risque materno-fœtal, Institut Fédératif de Recherche 136 Agents Transmissibles et Infectiologie, UFR Médecine, Université François Rabelais de Tours, Tours, France
⨯
Marie-Frédérique Lartigue,

Affiliations Equipe d'Accueil 3854 Bactéries et risque materno-fœtal, Institut Fédératif de Recherche 136 Agents Transmissibles et Infectiologie, UFR Médecine, Université François Rabelais de Tours, Tours, France, Service de Bactériologie et Hygiène Hospitalière, Hôpital Trousseau, CHRU de Tours, Tours, France
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Isabelle Virlogeux-Payant,

Affiliation Institut National de la Recherche Agronomique UR1282 Infectiologie Animale et Santé Publique, Nouzilly, France
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Roland Quentin,

Affiliations Equipe d'Accueil 3854 Bactéries et risque materno-fœtal, Institut Fédératif de Recherche 136 Agents Transmissibles et Infectiologie, UFR Médecine, Université François Rabelais de Tours, Tours, France, Service de Bactériologie et Hygiène Hospitalière, Hôpital Trousseau, CHRU de Tours, Tours, France
⨯
Agnès Rosenau

* E-mail: rosenau@univ-tours.fr

Affiliations Equipe d'Accueil 3854 Bactéries et risque materno-fœtal, Institut Fédératif de Recherche 136 Agents Transmissibles et Infectiologie, UFR Médecine, Université François Rabelais de Tours, Tours, France, Service de Bactériologie et Hygiène Hospitalière, Hôpital Trousseau, CHRU de Tours, Tours, France
⨯

Two-Component System RgfA/C Activates the fbsB Gene Encoding Major Fibrinogen-Binding Protein in Highly Virulent CC17 Clone Group B Streptococcus

Rim Al Safadi,
Laurent Mereghetti,
Mazen Salloum,
Marie-Frédérique Lartigue,
Isabelle Virlogeux-Payant,
Roland Quentin,
Agnès Rosenau

Published: February 4, 2011
https://doi.org/10.1371/journal.pone.0014658

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Fibrinogen
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Mutant strains
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DNA transcription
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Regulator genes
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Polymerase chain reaction
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Gene regulation
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Streptococcus agalactiae
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