Detection of Somatic Mutations by High-Resolution DNA Melting (HRM) Analysis in Multiple Cancers

Jesus Gonzalez-Bosquet; Jacob Calcei; Jun S. Wei; Montserrat Garcia-Closas; Mark E. Sherman; Stephen Hewitt; Joseph Vockley; Jolanta Lissowska; Hannah P. Yang; Javed Khan; Stephen Chanock

doi:10.1371/journal.pone.0014522

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Open Access

Peer-reviewed

Research Article

Detection of Somatic Mutations by High-Resolution DNA Melting (HRM) Analysis in Multiple Cancers

Jesus Gonzalez-Bosquet,

Affiliation Laboratory of Translational Genomics, Department of Health and Human Services (DHHS), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland, United States of America
⨯
Jacob Calcei,

Affiliation Laboratory of Translational Genomics, Department of Health and Human Services (DHHS), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland, United States of America
⨯
Jun S. Wei,

Affiliation Advanced Technology Center, Pediatric Oncology Branch, Center for Cancer Research, DHHS, NCI, NIH, Bethesda, Maryland, United States of America
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Montserrat Garcia-Closas,

Affiliation Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, DHHS, NCI, NIH, Bethesda, Maryland, United States of America
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Mark E. Sherman,

Affiliation Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, DHHS, NCI, NIH, Bethesda, Maryland, United States of America
⨯
Stephen Hewitt,

Affiliation Tissue Array Research Program, DHHS, NCI, NIH, Bethesda, Maryland, United States of America
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Joseph Vockley,

Affiliation Office of Cancer Genomics, DHHS, NCI, NIH, Bethesda, Maryland, United States of America
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Jolanta Lissowska,

Affiliation Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Institute of Oncology and Cancer Center, Warsaw, Poland
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Hannah P. Yang,

Affiliation Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, DHHS, NCI, NIH, Bethesda, Maryland, United States of America
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Javed Khan,

Affiliation Advanced Technology Center, Pediatric Oncology Branch, Center for Cancer Research, DHHS, NCI, NIH, Bethesda, Maryland, United States of America
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Stephen Chanock

* E-mail: chanocks@mail.nih.gov

Affiliation Laboratory of Translational Genomics, Department of Health and Human Services (DHHS), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland, United States of America
⨯

Detection of Somatic Mutations by High-Resolution DNA Melting (HRM) Analysis in Multiple Cancers

Jesus Gonzalez-Bosquet,
Jacob Calcei,
Jun S. Wei,
Montserrat Garcia-Closas,
Mark E. Sherman,
Stephen Hewitt,
Joseph Vockley,
Jolanta Lissowska,
Hannah P. Yang,
Javed Khan

Published: January 17, 2011
https://doi.org/10.1371/journal.pone.0014522

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