Paradoxical Increase in TAG and DAG Content Parallel the Insulin Sensitizing Effect of Unilateral DGAT1 Overexpression in Rat Skeletal Muscle

Silvie Timmers; Johan de Vogel-van den Bosch; Matthijs K. C. Hesselink; Denis van Beurden; Gert Schaart; Maria Joao Ferraz; Mario Losen; Pilar Martinez-Martinez; Marc H. De Baets; Johannes M. F. G. Aerts; Patrick Schrauwen

doi:10.1371/journal.pone.0014503

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Peer-reviewed

Research Article

Paradoxical Increase in TAG and DAG Content Parallel the Insulin Sensitizing Effect of Unilateral DGAT1 Overexpression in Rat Skeletal Muscle

Silvie Timmers ,

Contributed equally to this work with: Silvie Timmers, Johan de Vogel-van den Bosch

Affiliations Top Institute Food and Nutrition (TIFN), Wageningen, The Netherlands, Department of Human Biology, Maastricht University, Maastricht, The Netherlands
⨯
Johan de Vogel-van den Bosch ,

Contributed equally to this work with: Silvie Timmers, Johan de Vogel-van den Bosch

Affiliations Top Institute Food and Nutrition (TIFN), Wageningen, The Netherlands, Department of Human Biology, Maastricht University, Maastricht, The Netherlands
⨯
Matthijs K. C. Hesselink,

Affiliation Human Movement Sciences, School for Nutrition, Toxicology and Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands
⨯
Denis van Beurden,

Affiliation Department of Human Biology, Maastricht University, Maastricht, The Netherlands
⨯
Gert Schaart,

Affiliation Human Movement Sciences, School for Nutrition, Toxicology and Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands
⨯
Maria Joao Ferraz,

Affiliation Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Mario Losen,

Affiliation Department of Neuroscience, School of Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
⨯
Pilar Martinez-Martinez,

Affiliation Department of Neuroscience, School of Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
⨯
Marc H. De Baets,

Affiliation Department of Neuroscience, School of Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
⨯
Johannes M. F. G. Aerts,

Affiliation Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Patrick Schrauwen

* E-mail: p.schrauwen@hb.unimaas.nl

Affiliations Top Institute Food and Nutrition (TIFN), Wageningen, The Netherlands, Department of Human Biology, Maastricht University, Maastricht, The Netherlands
⨯

Paradoxical Increase in TAG and DAG Content Parallel the Insulin Sensitizing Effect of Unilateral DGAT1 Overexpression in Rat Skeletal Muscle

Silvie Timmers,
Johan de Vogel-van den Bosch,
Matthijs K. C. Hesselink,
Denis van Beurden,
Gert Schaart,
Maria Joao Ferraz,
Mario Losen,
Pilar Martinez-Martinez,
Marc H. De Baets,
Johannes M. F. G. Aerts

Published: January 14, 2011
https://doi.org/10.1371/journal.pone.0014503

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