A Novel HMM-Based Method for Detecting Enriched Transcription Factor Binding Sites Reveals RUNX3 as a Potential Target in Pancreatic Cancer Biology

• Liron Levkovitz,

  Affiliations Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, School of Computer Science, Tel Aviv University, Tel Aviv, Israel

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• Nir Yosef,

  Affiliation School of Computer Science, Tel Aviv University, Tel Aviv, Israel

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• Marvin C. Gershengorn,

  Affiliation Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Eytan Ruppin,

  Affiliations Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, School of Computer Science, Tel Aviv University, Tel Aviv, Israel

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• Roded Sharan ,

  Contributed equally to this work with: Roded Sharan, Yoram Oron

  * E-mail: roded@post.tau.ac.il (RS); medfair@post.tau.ac.il (YO)

  Affiliation School of Computer Science, Tel Aviv University, Tel Aviv, Israel

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• Yoram Oron

  Contributed equally to this work with: Roded Sharan, Yoram Oron

  * E-mail: roded@post.tau.ac.il (RS); medfair@post.tau.ac.il (YO)

  Affiliation Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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