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Open Access
Peer-reviewed
Research Article
Genetic Variants in Toll-Like Receptors Are Not Associated with Rheumatoid Arthritis Susceptibility or Anti-Tumour Necrosis Factor Treatment Outcome
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Marieke J. H. Coenen ,
Contributed equally to this work with: Marieke J. H. Coenen, Christian Enevold
* E-mail: m.coenen@antrg.umcn.nl
Affiliation Department of Human Genetics, Radboud University Nijmegen Medical Centre, Institute for Genetic and Metabolic Disease (IGMD), Nijmegen, The Netherlands
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Christian Enevold ,
Contributed equally to this work with: Marieke J. H. Coenen, Christian Enevold
Affiliation Department of Rheumatology, Institute for Inflammation Research, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
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Pilar Barrera,
Affiliation Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
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Mascha M. V. A. P. Schijvenaars,
Affiliation Department of Human Genetics, Radboud University Nijmegen Medical Centre, Institute for Genetic and Metabolic Disease (IGMD), Nijmegen, The Netherlands
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Erik J. M. Toonen,
Affiliation Department of Human Genetics, Radboud University Nijmegen Medical Centre, Institute for Genetic and Metabolic Disease (IGMD), Nijmegen, The Netherlands
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Hans Scheffer,
Affiliation Department of Human Genetics, Radboud University Nijmegen Medical Centre, Institute for Genetic and Metabolic Disease (IGMD), Nijmegen, The Netherlands
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Leonid Padyukov,
Affiliation Rheumatology Unit, Department of Medicine, Karolinska Institutet at Karolinska University Hospital Solna, Stockholm, Sweden
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Alf Kastbom,
Affiliation Division of Rheumatology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden
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Lars Klareskog,
Affiliation Rheumatology Unit, Department of Medicine, Karolinska Institutet at Karolinska University Hospital Solna, Stockholm, Sweden
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Anne Barton,
Affiliation Arthritis Research Campaign Epidemiology Unit, The University of Manchester, Manchester, United Kingdom
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Wietske Kievit ,
¶b Participating on behalf of the DREAM registry.
Affiliation Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
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Maarten J. Rood ,
¶b Participating on behalf of the DREAM registry.
Affiliation Department of Rheumatology, Ziekenhuis Gelderse Vallei, Ede, The Netherlands
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Tim L. Jansen ,
¶b Participating on behalf of the DREAM registry.
Affiliation Department of Rheumatology, Medical Centre Leeuwarden, Leeuwarden, The Netherlands
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Dorine Swinkels ,
¶a Participating on behalf of the Nijmegen Biomedical Study.
Affiliation Laboratory of Clinical Chemistry, Laboratory Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
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Piet L. C. M. van Riel ,
¶b Participating on behalf of the DREAM registry.
Affiliation Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
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Barbara Franke ,
¶a Participating on behalf of the Nijmegen Biomedical Study.
Affiliation Department of Human Genetics, Radboud University Nijmegen Medical Centre, Institute for Genetic and Metabolic Disease (IGMD), Nijmegen, The Netherlands
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Klaus Bendtzen,
Affiliation Department of Rheumatology, Institute for Inflammation Research, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
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Timothy R. D. J. Radstake
Affiliation Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
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Genetic Variants in Toll-Like Receptors Are Not Associated with Rheumatoid Arthritis Susceptibility or Anti-Tumour Necrosis Factor Treatment Outcome
- Marieke J. H. Coenen,
- Christian Enevold,
- Pilar Barrera,
- Mascha M. V. A. P. Schijvenaars,
- Erik J. M. Toonen,
- Hans Scheffer,
- Leonid Padyukov,
- Alf Kastbom,
- Lars Klareskog,
- Anne Barton
- Published: December 15, 2010
- https://doi.org/10.1371/journal.pone.0014326