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Open Access

Peer-reviewed

Research Article

Endothelial Surface Layer Degradation by Chronic Hyaluronidase Infusion Induces Proteinuria in Apolipoprotein E-Deficient Mice

Marijn C. Meuwese ,

Contributed equally to this work with: Marijn C. Meuwese, Lysette N. Broekhuizen

Affiliation Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands
⨯
Lysette N. Broekhuizen ,

Contributed equally to this work with: Marijn C. Meuwese, Lysette N. Broekhuizen

* E-mail: h.vink@fys.unimaas.nl

Affiliation Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands
⨯
Mayella Kuikhoven,

Affiliation Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Netherlands
⨯
Sylvia Heeneman,

Affiliation Department of Pathology, Cardiovascular Research Institute Maastricht, Maastricht University, Netherlands
⨯
Esther Lutgens,

Affiliation Department of Pathology, Cardiovascular Research Institute Maastricht, Maastricht University, Netherlands
⨯
Marion J. J. Gijbels,

Affiliations Department of Pathology, Cardiovascular Research Institute Maastricht, Maastricht University, Netherlands, Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, Netherlands
⨯
Max Nieuwdorp,

Affiliation Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands
⨯
Carine J. Peutz,

Affiliation Department of Pathology, Cardiovascular Research Institute Maastricht, Maastricht University, Netherlands
⨯
Erik S. G. Stroes,

Affiliation Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands
⨯
Hans Vink,

Affiliations Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands, Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Netherlands
⨯
Bernard M. van den Berg

Affiliation Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Netherlands
⨯

Endothelial Surface Layer Degradation by Chronic Hyaluronidase Infusion Induces Proteinuria in Apolipoprotein E-Deficient Mice

Marijn C. Meuwese,
Lysette N. Broekhuizen,
Mayella Kuikhoven,
Sylvia Heeneman,
Esther Lutgens,
Marion J. J. Gijbels,
Max Nieuwdorp,
Carine J. Peutz,
Erik S. G. Stroes,
Hans Vink

x

Published: December 8, 2010
https://doi.org/10.1371/journal.pone.0014262

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