Hepatitis C Virus Core Protein Abrogates the DDX3 Function That Enhances IPS-1-Mediated IFN–Beta Induction

• Hiroyuki Oshiumi,

  Affiliation Department of Microbiology and Immunology, Hokkaido University Graduate School of Medicine, Sapporo, Japan

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• Masanori Ikeda,

  Affiliation Department of Tumor Virology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan

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• Misako Matsumoto,

  Affiliation Department of Microbiology and Immunology, Hokkaido University Graduate School of Medicine, Sapporo, Japan

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• Ayako Watanabe,

  Affiliation Department of Microbiology and Immunology, Hokkaido University Graduate School of Medicine, Sapporo, Japan

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• Osamu Takeuchi,

  Affiliation Laboratory of Host Defense, WPI Immunology Frontier Research Center, Research Institute for Microbial Diseases, Osaka University, Suita, Japan

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• Shizuo Akira,

  Affiliation Laboratory of Host Defense, WPI Immunology Frontier Research Center, Research Institute for Microbial Diseases, Osaka University, Suita, Japan

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• Nobuyuki Kato,

  Affiliation Department of Tumor Virology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan

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• Kunitada Shimotohno,

  Affiliation Research Institute, Chiba Institute of Technology, Narashino, Japan

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• Tsukasa Seya

  * E-mail: seya-tu@pop.med.hokudai.ac.jp

  Affiliation Department of Microbiology and Immunology, Hokkaido University Graduate School of Medicine, Sapporo, Japan

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