Genistein Improves Neuropathology and Corrects Behaviour in a Mouse Model of Neurodegenerative Metabolic Disease

• Marcelina Malinowska ,

  Contributed equally to this work with: Marcelina Malinowska, Fiona L. Wilkinson

  Affiliations Mucopolysaccharidosis (MPS) Stem Cell Research Group, Biomedicine, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom, Department of Molecular Biology, Faculty of Biology, University of Gdansk, Gdansk, Poland

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• Fiona L. Wilkinson ,

  Contributed equally to this work with: Marcelina Malinowska, Fiona L. Wilkinson

  Affiliation Mucopolysaccharidosis (MPS) Stem Cell Research Group, Biomedicine, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom

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• Kia J. Langford-Smith,

  Affiliation Mucopolysaccharidosis (MPS) Stem Cell Research Group, Biomedicine, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom

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• Alex Langford-Smith,

  Affiliation Mucopolysaccharidosis (MPS) Stem Cell Research Group, Biomedicine, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom

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• Jillian R. Brown,

  Affiliation Zacharon Pharmaceuticals Inc., San Diego, California, United States of America

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• Brett E. Crawford,

  Affiliation Zacharon Pharmaceuticals Inc., San Diego, California, United States of America

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• Marie T. Vanier,

  Affiliation Institut National de la Santé et de la Recherche Médicale (INSERM) Unit 820, Lyon University, Lyon, France

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• Grzegorz Grynkiewicz,

  Affiliation Pharmaceutical Research Institute, Warsaw, Poland

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• Rob F. Wynn,

  Affiliation Bone Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester Academic Health Science Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom

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• J. Ed Wraith,

  Affiliation Genetic Medicine, St. Mary's Hospital, Manchester Academic Health Science Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom

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• Grzegorz Wegrzyn,

  Affiliation Department of Molecular Biology, Faculty of Biology, University of Gdansk, Gdansk, Poland

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• Brian W. Bigger

  * E-mail: Brian.Bigger@manchester.ac.uk

  Affiliations Mucopolysaccharidosis (MPS) Stem Cell Research Group, Biomedicine, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom, Bone Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester Academic Health Science Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom

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